Wheeling Park raced out to 39-13 halftime lead over Parkersburg and held on in the second half to win 68-51.
Emily Puskarich led the Patriots with 30 while Haley Robb added 26.
Park will meet Parkersburg South in the sectional final, Friday in Parkersburg.
South defeated Brooke 76-49. Park and South split their two regular season meetings with the home team winning both.