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Protea expands patent platform

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Protea Biosciences Group has awarded George Washington University two additional patents for its LAESI technology platform, for which Protea is the exclusive licensee. The first patent is "Laser Ablation Electrospray Ionization (LAESI) for Atmospheric Pressure, In Vivo, and Imaging Mass Spectrometry" (U.S. Patent 8,487,244). The second patent is "Three Dimensional Molecular Imaging By Infrared Laser Ablation Electrospray Ionization Mass Spectrometry" (U.S. Patent 8,487,246). Both patents were issued on July 16.

"We are pleased that these two additional patents have been issued", said Steve Turner, Protea's CEO. "LAESI represents a revolutionary technology to rapidly identify the molecular products of living cells, due to its ability to perform two dimensional and three dimensional molecular imaging, all without sample preparation or the addition of chemical matrices. Even live cells and bacterial colonies can be analyzed with LAESI.  Collectively these capabilities will prove invaluable to pharmaceutical and life science research laboratories worldwide."

LAESI-MS (Laser Ablation Electrospray Ionization-Mass Spectrometry) was invented in the laboratory of Akos Vertes, Ph.D., professor of chemistry at the George Washington University and exclusively licensed to Protea. LAESI enables rapidly obtaining mass spectrometry data profiles of bio-molecules present in cells. LAESI analysis can be performed on tissue sections identical to those used in traditional histological staining and examination without the need for sample preparation that can lead to sample loss and contamination. LAESI enables the generation of direct, rapid and reproducible data, decreasing both the time and cost to obtain mass spectrometric analysis of biological samples.

Protea's area of study is mass spectrometry molecular imaging – the identification and localization of the molecular products of living cells, that is foundational science for all pharmaceutical, medical, and life science research.